Forced Vital Capacity (FVC) decline, mortality and healthcare resource utilization in idiopathic pulmonary fibrosis

Relative versus absolute change in forced vital capacity in idiopathic pulmonary fibrosis.

BACKGROUND Decline in forced vital capacity (FVC) over time reliably predicts mortality in patients with idiopathic pulmonary fibrosis. The use of this measure in clinical practice is recommended by current evidence-based guidelines. It is unknown if the method of calculating decline in FVC (relative vs. absolute change) impacts its frequency or its ability to predict mortality. METHODS Patie...

Forced Vital Capacity (FVC) and Forced Vital Capacity in 1 Second (FEV1) of Apparently Healthy Non-smoker Adult Obese

Change in forced vital capacity and associated subsequent outcomes in patients with newly diagnosed idiopathic pulmonary fibrosis.

BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a rare and serious disease characterized by progressive lung-function loss. Limited evidence has been published on the impact of lung-function loss on subsequent patient outcomes. This study examined change in forced vital capacity (FVC) across IPF patients in the 6 months after diagnosis and its association with clinical and healthcare resource...

Normal values of forced vital capacity (FVC), forced expiratory volume (FEV 1-0), and peak flow rate (PFR) in children.

In children, the respiratory tract is probably more often affected by disease than any other system of the body. In spite of this, quantitative methods of evaluation are seldom used outside special respiratory units. No clinician would manage a patient with potential renal failure without laboratory aids, even if it were only an estimation of the blood urea, but he would seldom give children wi...

Forced vital capacity (FVC) as an indicator of survival and disease progression in an ALS clinic population.

In a large cohort of 1034 patients with the diagnosis of definite or probable amyotrophic lateral sclerosis (ALS), the association of forced vital capacity (FVC) at baseline with (a) time to progression of 20 points in Appel ALS (AALS) score or (b) tracheostomy free survival was investigated. The median survival of ALS patients with baseline FVC <75% was 2.91 years, compared with 4.08 years for...